Aborted Pediatric HIV vaccines likely to offer some protection from the virus
A recent acknowledgement conducted from the research of HIV vaccines stated that, the pediatric HIV vaccines, which were earlier aborted proves to be effective in the prevention of the risk caused due to the infection. The acknowledgment was published by the researchers of The Journal of Infectious Diseases, subsequent to conducting a research on the two failed HIV vaccines, which were earlier tested in the year 1990.
Initially, these vaccines proved to be ineffective as they failed to elicit BNAs, i.e. broadly neutralizing antibodies when given to the infants. However, after the recent research was conducted, it was discovered that these vaccines protected against HIV by eliciting antibodies, which get attached to the outer envelope of the HIV, as opposed to eliciting the BNAs. Subsequent to this, the researchers went on to trying the vaccines, which were earlier tested in 1990.
On conducting the research it was discovered that 59 percent infants were given the vaccination of VaxGen and about 79 percent of the same age group who were given Chiron vaccine gathered the immunity against this infection. Even as they turned a year older, they still had the effect of the vaccination intact in their body.
The authors of the research commented that, “it is reassuring to know that the effect of these old vaccinations stayed in the body of the infants for long. This proves to be helpful, as during the initial years of a child, the chances of catching the infection from the mother through breast feeding is quite high. If the vaccination provides protection for the initial 2 years too, it would be beneficial for the child.”
This research has motivated the scientists to further work on developing new vaccinations that can render better protection than those which were tested earlier. These vaccinations if given at an early age can provide protective antibody and long-lasting response during the critical years of a child’s life.